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"基质金属蛋白酶(MMPs)是一组含有活性Zn2+的蛋白水解酶,所以" 的 英語 翻譯

基质金属蛋白酶(MMPs)是一组含有活性Zn2+的蛋白水解酶,所以称为金属蛋白酶,依据催化区结构的不同可分为许多组。MMPs最初被认为是作用于细胞外基质的一组蛋白酶,然而之后的许多体内实验发现它同样会作用于许多非细胞外基质蛋白。由于作用底物的多样性,MMPs参与了许多与自身稳定相关的功能,例如组织修复、免疫及病理过程,包括肿瘤、纤维化和感染。

Matrix metalloproteinases (MMPs) are a group of proteolytic enzymes containing active zinc ions, so they are called metalloproteinases. They can be divided into many groups according to the structure of catalytic region. MMPs were initially considered as a group of proteases acting on extracellular matrix, but many in vivo experiments have found that they also act on many non-fine proteases. Extracellular matrix proteins. Due to the diversity of substrates, MMPs are involved in many functions related to self-stabilization, such as tissue repair, immune and pathological processes, including tumors, fibrosis and infection.

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